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<html lang="en" class="story nytapp-vi-article nytapp-vi-story g-page-production g-viewport-xxsmall g-viewport-xsmall g-viewport-small g-viewport-medium g-viewport-large g-viewport-xlarge g-viewport-xxlarge g-page-isdesktop g-page-islandscape g-page-iswidescreen g-page-islargescreen story nytapp-vi-article " data-nyt-compute-assignment="fallback" xmlns:og="http://opengraphprotocol.org/schema/" data-rh="lang,class"><head> <meta charset="utf-8"> <title>CRISPR, 10 Years On: Learning to Rewrite the Code of Life - The New York Times</title> <meta data-rh="true" name="robots" content="noarchive, max-image-preview:large"><meta data-rh="true" name="description" content="The gene-editing technology has led to innovations in medicine, evolution and agriculture β and raised profound ethical questions about altering human DNA."><meta data-rh="true" property="twitter:url" content="https://www.nytimes.com/2022/06/27/science/crispr-gene-editing-10-years.html"><meta data-rh="true...
Ten years ago this week, Jennifer Doudna and her colleagues published the results of a test-tube experiment on bacterial genes. When the study came out in the journal Science on June 28, 2012, it did not make headline news. In fact, over the next few weeks, it did not make any news at all.Looking back, Dr. Doudna wondered if the oversight had something to do with the wonky title she and her colleagues had chosen for the study: βA Programmable Dual RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity.ββI suppose if I were writing the paper today, I would have chosen a different title,β Dr. Doudna, a biochemist at the University of California, Berkeley, said in an interview.Far from an esoteric finding, the discovery pointed to a new method for editing DNA, one that might even make it possible to change human genes.βI remember thinking very clearly, when we publish this paper, itβs like firing the starting gun at a race,β she said.In just a decade, CRISPR has become one of the most...
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